GRK7 Antibody，Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) GRK7 Polyclonal antibody
Uniprot No.：

Q8WTQ7
基因名：

GRK7
別名：

GRK7 antibody; GPRK7 antibody; Rhodopsin kinase GRK7 antibody; EC 2.7.11.14 antibody; G protein-coupled receptor kinase 7 antibody; G protein-coupled receptor kinase GRK7 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Rhodopsin kinase protein (342-550AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Antigen Affinity purified & Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).
基因功能參考文獻：
1. Defects in GRK1 or GRK7 cause patients to suffer from an inability to properly deactivate rhodopsin leading to problems with recovery and dark adaptation. PMID: 22183412
2. Phosphorylation of GRK1 and GRK7 by PKA occurs in the dark, when cAMP levels in photoreceptor cells are elevated. PMID: 15946941
3. synthesis of 29 of GRK1 or GRK7 partial peptides that cover the entire sequence of GRK1/GRK7, to see which interacts with recoverin. PMID: 18266817
亞細胞定位：

Membrane; Lipid-anchor.
蛋白家族：

Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily
組織特異性：

Retinal cones, outer and inner segments.
數據庫鏈接：

HGNC: 17031

OMIM: 606987

KEGG: hsa:131890

STRING: 9606.ENSP00000264952

UniGene: Hs.680654

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